Disposable Negative Pressure Chamber


N P S (Negative Pressure SteriDome) is our contribution to the fight against pandemics and contagious diseases like COVID-19. BSI has taken a decade of isolation tech and biocontainment R&D to create the world's first disposable negative pressure isolation chamber.


N P S helps contain COVID-19 aerosols during by placing the patient’s head inside a clear and comfy disposable negative pressure isolation chamber with patented air-locks for robust biosafety and infection control.

NPS Inquiries: 

Containing COVID-19

SARS-CoV-2, the virus that causes COVID-19, can cause severe respiratory illness to humans infected by the virus, with the most common symptoms being fever, dry cough, and tiredness. Healthcare providers and hospital patients are facing a high risk of sickness and exposure to infectious agents such as the COVID-19 virus. Thousands of U.S. healthcare workers continue to be infected and more than 600 have passed away due to exposure from aerosolized virus that is being spread on all surfaces and clothing. Makeshift solutions such as boxes and drapes, pictured here, are not enough.

NPS is the right solution - it's easy to use, flexible, has access for tools, and safer for everyone.

The State of the Art: Still Inside The Box

Current solutions are open containers, such as rigid acrylic boxes and drapes.


These solutions are inadequate and pose undue risk to patients and providers. They “decrease rather than increase safety, especially under emergency conditions”...and “does not reduce risk, and probably has unintended safety consequences” since “the box probably redirects droplets and aerosols toward the foot of the bed, and all staff in the room are still exposed to them” - Yale anesthesiologists Dr. William H. Rosenblatt and Dr. Jodi D. Sherman in a recent letter to the New England Journal of Medicine (https://www.nejm.org/doi/full/10.1056/NEJMc2012960)

NPS is a disposable, clear, flexible structure made of plastic having an ergonomic and robust design and is intended for use as a practical isolation hood for HCP while being ultra-lightweight and compact to transport at high volume. It has a large access door, and a two-way air-lock system to allow transport of tools without compromising the internal environment - making it the the ideal enclosure that is easy to use with no structural gaps. 

A recent trial conducted at Boston Medical Center compared the use of standard personal protective equipment (PPE) to a makeshift “aerosol box” during simulated patient intubation. These makeshift aerosol boxes (aerosol boxes) are being widely used, however, these aerosol boxes require training, are cumbersome and can potentially injure patients or providers if dropped.


NPS has been developed with HCP user input, weighs only 1lb and can be used with limited training. NPS allows for visual observations, manipulation, insertion, and/or removal of items (e.g. medical tools, medicines, etc.) within the interior space of the NPS through one or more particular sleeves while providing a Protective Barrier Enclosure for HCP as an extra layer of protection for transport and aerosol producing procedures, making this device a safe alternative for patients and HCP. 

BSI believes NPS is more effective than current solutions that have major structural gaps which let the virus  escape. Disposability of the NPS also provides an advantage by reducing the amount of cross-contamination compared to current drapes and boxes, in addition to providing an extra layer of protection to HCP as an isolation hood for patients, while giving patients, a safe, airy space to comfortably recover in.

keywords: Aerosol Hood, NPS, Negative PRessure SteriDome, Covid-19, aerosol boxes, Breegi Scientific

Breegi Scientific Inc. is a socially conscious innovator engineering safe, affordable, easy to use biocontainment solutions.

Breegi Scientific, Inc,

All rights reserved

  • LinkedIn
  • Facebook


730 Commonwealth Ave.

Brookine, MA 02466